reproductive system disorder diethylstilbestrol syndrome https://github.com/monarch-initiative/mondo/issues/6753 https://rarediseases.info.nih.gov/diseases/1859/diethylstilbestrol-syndrome https://www.malacards.org/card/diethylstilbestrol_syndrome MONDO:0016012 diethylstilbestrol embryofetopathy antenatal diethylstilbestrol exposure UMLS:C0853695 Orphanet:1916 SCTID:716005004 foetal diethylstilbestrol syndrome DOID:0051077 Diethylstilbestrol (DES) syndrome is a malformation syndrome reported in offspring (children and grandchildren) of women exposed to DES during pregnancy and is characterized by reproductive tract malformations, decreased fertility and increased risk of developing clear cell carcinoma of the vagina and cervix in young women. Reproductive malformations reported in DES syndrome include small, T-shaped uteri and other uterotubal anomalies that increase the risk of miscarriages in women and epididymal cysts, microphallus, cryptorchidism, or testicular hypoplasia in men. DES, a synthetic nonsteroidal estrogen was widely prescribed from 1940-1970 to prevent miscarriage. DES embryofetopathy icd11.foundation:1134098724 MedDRA:10012780 DES syndrome NCIT:C113422 Distilbene embryofetopathy MEDGEN:799290 fetal diethylstilbestrol syndrome toxic or drug-related embryofetopathy