toluene embryopathy https://github.com/monarch-initiative/mondo/issues/3680 https://www.malacards.org/card/toluene_embryopathy toluene embryopathy MESH:C538114 UMLS:C2931737 Orphanet:1920 MEDGEN:444131 Toluene embryopathy is a neurodevelopmental teratologic syndrome due to prenatal exposure to toluene. The disease is characterized by prematurity, low birth weight, dysmorphic features (short palpebral fissures, deep set eyes, low set ears, mid-facial hypoplasia, flat nasal bridge, thin upper lip, micrognathia, spatulate fingertips and small fingernails), central nervous system dysfunctions (intellectual disability, microcephaly, language impairment, hyperactivity, visual dysfunction) and postnatal growth delay. Prenatal exposure to toluene occurs as a result of incidental occupational exposure or solvent abuse during pregnancy. The features of toluene embryopathy often overlap with those seen in fetal alcohol syndrome. microcephaly, central nervous system dysfunction, minor craniofacial and limb anomalies, and variable growth deficiency GARD:0018751 MONDO:0016016 Hersh Podruch Weisskopk syndrome icd11.foundation:1446076607 toxic or drug-related embryofetopathy neurodevelopmental disorder