isolated encephalocele https://www.malacards.org/card/isolated_encephalocele bifid cranium NORD:1089 GARD:0006333 cranium bifidum Encephalocele Brain tissue herniation through a congenital or acquired defect in the skull. The majority of congenital encephaloceles occur in the occipital or frontal regions. Clinical features include a protuberant mass that may be pulsatile. The quantity and location of protruding neural tissue determines the type and degree of neurologic deficit. Visual defects, psychomotor developmental delay, and persistent motor deficits frequently occur. MONDO:0016057 Orphanet:199647 craniocele UMLS:C5680519 MEDGEN:1830107 MedDRA:10014617 encephalocele cephalocele