autosomal dominant disease intestinal polyposis syndrome hereditary neoplastic syndrome Cowden disease https://www.malacards.org/card/cowden_syndrome CD Orphanet:201 SCTID:58037000 A genodermatosis characterized by the presence of multiple hamartomas in various tissues and an increased risk for malignancies of the breast, thyroid, endometrium, kidney and colorectum. When CS is accompanied by germline PTEN mutations, it belongs to the PTEN hamartoma tumor syndrome (PHTS) group. MEDGEN:5420 MHAM OMIMPS:158350 MONDO:0016063 UMLS:C0018553 MedDRA:10051906 NCIT:C3076 MESH:D006223 GARD:0006202 Cowden disease Cowden syndrome multiple hamartoma syndrome Cowden's disease NANDO:2200918 DOID:6457 PTEN hamartoma tumor syndrome hereditary skin disorder