congenital systemic arteriovenous fistula https://github.com/monarch-initiative/mondo/issues/5963 https://www.malacards.org/card/congenital_systemic_arteriovenous_fistula MONDO:0016078 GARD:0018758 A rare, potentially life-threatening, vascular disease characterized by a direct communication between an artery and a vein, without the interposition of the capillary bed, ocurring in the systemic circulation (mainly the cranium, liver, lungs, extremities, and vessels in or near the thoracic wall). Manifestations are variable depending on size and extent of the fistula, the involved blood vessels and the precise location of the collaterals and may include systolic or continuous murmur over the affected organ, tachycardia, increased stroke volume, cardiomegaly and increased pulmonary vascular markings. Orphanet:2039 MEDGEN:1679454 UMLS:C5191839 congenital arteriovenous fistula