integumentary system disorder obsolete syndromic diaphragmatic or abdominal wall malformation cutis laxa https://github.com/monarch-initiative/mondo/issues/6749 https://rarediseases.info.nih.gov/diseases/6227/cutis-laxa https://www.malacards.org/card/cutis_laxa NCIT:C84663 generalized elastolysis Cutis laxa (CL) is an inherited or acquired connective tissue disorder characterized by wrinkled, redundant and sagging inelastic skin associated with skeletal and developmental anomalies and, in some cases, with severe systemic involvement. Several different forms of inherited CL have been described, differentiated on the basis of the mode of inheritance and differences in the extent of internal organ involvement, associated anomalies and disease severity. generalised elastolysis NORD:1022 cutis laxa GARD:0006227 UMLS:C0010495 SCTID:58588007 icd11.foundation:1227401566 MedDRA:10011692 Orphanet:209 MESH:D003483 DOID:3144 MEDGEN:8206 elastolysis MONDO:0016175 developmental defect during embryogenesis congenital entropion