leukonychia totalis-acanthosis-nigricans-like lesions-abnormal hair syndrome https://www.malacards.org/card/leukonychia_totalis_acanthosis_nigricans_like_lesions_abnormal_hair_syndrome UMLS:C4751169 GARD:0020448 MEDGEN:1654873 MONDO:0016213 Orphanet:210133 Leukonychia totalis-acanthosis-nigricans-like lesions-abnormal hair syndrome is a rare, syndromic nail anomaly disorder characterized by the association of leukonychia totalis with acanthosis-nigricans-like lesions (occurring in the neck, axillae and abdomen regions) and hair dysplasia, manifesting with dry, brittle hair which presents an irregular pattern of complete or incomplete twists and an irregular surface with londitudinal furrows on electronic microscopy. hyperpigmentation of the skin