maternal hyperthermia induced birth defects https://github.com/monarch-initiative/mondo/issues/6876 https://rarediseases.info.nih.gov/diseases/2856/hyperthermia-induced-defects https://www.malacards.org/card/maternal_hyperthermia_induced_birth_defects MEDGEN:1631447 GARD:0002856 SCTID:765138001 MONDO:0016378 UMLS:C4707329 icd11.foundation:1917022285 hyperthermia induced defects Orphanet:2216 Maternal hyperthermia induced birth defects is a rare maternal disease-related embryofetopathy characterized by variable developmental anomalies of the fetus due to teratogenic effect of elevated maternal body temperature (resulting from febrile illness or hot environment exposure). Reported developmental anomalies include neural tube defects (spina bifida, ecephalocele, anencephaly), cardiac defects (transposition of great vessels), urogenital defects (hypospadias), abdominal wall defects, cleft lip/palate, eye defects (cataract, coloboma) or various minor anomalies (e.g., bifid uvula, preauricular pit or tag). Consensus regarding cause-effect relationship has not been reached. disorder of development or morphogenesis