has characteristic has characteristic primary aldosteronism hyperaldosteronism hereditary disease familial hyperaldosteronism https://www.malacards.org/card/familial_hyperaldosteronism https://www.malacards.org/card/genetic_hyperaldosteronism UMLS:C3713420 MESH:C580087 hereditary hyperaldosteronism Orphanet:235936 GARD:0020630 genetic hyperaldosteronism Orphanet:371861 MEDGEN:780028 OMIMPS:103900 MONDO:0016525 NCIT:C127160 SCTID:703231005 FH Familial hyperaldosteronism (FH) is the heritable form of primary aldosteronism (PA) which comprises three identified subtypes to date: FH type I (FH-I) characterized by early-onset hypertension, glucocorticoid remediable adrenocorticotropic hormone (ACTH)-dependent hyperaldosteronism, variable hypokalemia, and overproduction of 18-oxocortisol and 18-hydroxycortisol; FH type II (FH-II) characterized by hypertension of varying severity and hyperaldosteronism not suppressible by dexamethasone; and FH type III (FH-III) characterized by profound hypokalemia, early-onset severe hypertension, non glucocorticoid-remediable hyperaldosteronism, and overproduction of 18-oxocortisol and 18-hydroxycortisol. icd11.foundation:1586992015 NANDO:2200602 inherited