filariasis loiasis https://rarediseases.info.nih.gov/diseases/3283/loiasis https://www.malacards.org/card/loiasis EFO:1000729 MedDRA:10024797 NCIT:C34784 icd11.foundation:709184369 African eye worm Loiasis is a form of filariasis (see this term), caused by the parasitic worm Loa loa, endemic to the forest and savannah regions of Central and Western Africa. Loiasis may either be asymptomatic or manifest as a large, transient area of localized, non-erythematous subcutaneous edema (Calabar swellings), adult worm migration through the sub-conjunctiva (''African eye worm'') and pruritus. Generalized itching, hives, muscle pains, arthralgias, fatigue, and adult worms visibly migrating under the surface of the skin may be observed. Severe complications such as encephalopathy have been reported in highly infected individuals receiving ivermectin during mass drug administration programs for the control of onchocerciasis and lymphatic filariasis. DOID:13523 GARD:0003283 MESH:D008118 Loa loa filariasis ICD10CM:B74.3 Orphanet:2404 ICD9:125.2 UMLS:C0023968 SCTID:44250009 MONDO:0016566 MEDGEN:6132