disease arises from structure disease arises from alteration in structure chromosome 5 (Human) ring chromosome 5 https://rarediseases.info.nih.gov/diseases/10841/ring-chromosome-5 https://www.malacards.org/card/ring_chromosome_5 Ring 5 Ring chromosome 5 syndrome is a rare chromosomal anomaly syndrome, with high phenotypic variability, principally characterized by a neonatal mewing cry, severe developmental delay and intellectual disability, short stature, hypotonia, dysmorphic features (incl. microcephaly, facial asymmetry, hypertelorism, epicanthal folds, abnormal ears, micro/retrognathia), congenital cardiac anomalies (such as atrial and ventricular septal defect, tricuspid insufficiency, hypoplastic aorta) and skeletal abnormalities (e.g. hypoplastic thumbs, anomalous ulna/radius, dysplastic metacarpals and phalanges). chromosome 5 ring SCTID:765487008 UMLS:C4050064 MONDO:0016654 NCIT:C121984 Orphanet:251043 R5 Ring chromosome 5 syndrome Ring chromosome type 5 MEDGEN:881956 GARD:0010841 rose cluster 5 chromosome 5 disorder ring chromosome disorder