disease arises from structure disease arises from alteration in structure chromosome Y (Human) ring chromosome Y https://www.malacards.org/card/ring_chromosome_y UMLS:C4706450 Ring chromosome type Y GARD:0020785 r(Y) MONDO:0016853 Ring chromosome Y is a rare chromosome Y structural anomaly, with a highly variable phenotype, mostly characterized by short stature, partial to total gonadal failure, sexual infantilism, genital anomalies (e.g. ambiguous genitalia, hypospadias, cryptorchidism), and azoospermia or oligozoospermia. Additional reported features include speech delay, obesity, and acanthosis nigricans. Gender dysphoria and comorbid bipolar disorder have also been observed. icd11.foundation:388539343 MEDGEN:1631964 SCTID:763407008 Orphanet:261529 Ring chromosome Y syndrome chromosome Y disorder ring chromosome disorder