disease arises from structure disease arises from alteration in structure 1p (Human) syndrome caused by partial chromosomal deletion partial deletion of chromosome 1 partial deletion of the short arm of chromosome 1 https://github.com/monarch-initiative/mondo/issues/3664 https://www.malacards.org/card/partial_deletion_of_the_short_arm_of_chromosome_1 1p monosomy 1p deletion Orphanet:261857 monosomy 1p MESH:C535591 chromosome 1p deletion Chromosome 1p deletion is a chromosome abnormality that occurs when there is a missing copy of the genetic material located on the short arm (p) of chromosome 1. The severity of the condition and the signs and symptoms depend on the size and location of the deletion and which genes are involved. Features that often occur in people with chromosome 1p deletion include developmental delay, intellectual disability, behavioral problems, and distinctive facial features. Most cases are not inherited, but people can pass the deletion on to their children. Treatment is based on the signs and symptoms present in each person. partial monosomy of the short arm of chromosome 1 MONDO:0016883 NCIT:C36501 partial monosomy 1p icd11.foundation:1004815242 UMLS:C0795796 partial deletion of chromosome 1p deletion 1p MEDGEN:208633 partial deletion of the short arm of chromosome type 1 partial monosomy of chromosome 1p