disease arises from structure disease arises from alteration in structure 15q (Human) syndrome caused by partial chromosomal duplication partial duplication of the long arm of chromosome 15 https://github.com/monarch-initiative/mondo/issues/3492 https://www.malacards.org/card/partial_duplication_of_the_long_arm_of_chromosome_15 MESH:C538040 partial trisomy 15q UMLS:C0795858 partial duplication of the long arm of chromosome type 15 trisomy 15q 15q trisomy Orphanet:262950 Duplication 15q partial trisomy of chromosome 15q Chromosome 15q duplication is a chromosome abnormality that occurs when an extra (duplicate) copy of the genetic material located on the long arm (q) of chromosome 15 is present in each cell. The severity of the condition and the associated signs and symptoms vary based on the size and location of the duplication and which genes are involved. Common features shared by many people with this duplication include developmental delay; intellectual disability; hypotonia (low muscle tone); seizures ; high and/or cleft palate (roof of the mouth); scoliosis ; slow growth; communication difficulties; behavioral problems; and distinctive facial features. Most cases are not inherited, although affected people can pass the duplication on to their children. Treatment is based on the signs and symptoms present in each person. MEDGEN:167076 chromosome 15q duplication partial duplication of chromosome 15q partial trisomy of the long arm of chromosome 15 MONDO:0016965 15q duplication