syndromic disease hereditary disease imperforate oropharynx-costo vetebral anomalies syndrome https://github.com/monarch-initiative/mondo/issues/6751 https://github.com/monarch-initiative/mondo/issues/6877 https://www.malacards.org/card/imperforate_oropharynx_costo_vertebral_anomalies_syndrome MONDO:0017162 UMLS:C4749770 imperforate oropharynx-costo vetebral anomalies GARD:0002989 Seghers syndrome Orphanet:2759 MEDGEN:1663228 Imperforate oropharynx-costovertebral anomalies syndrome is a dysostosis with predominant vertebral and costal involvement characterized by oropharyngeal atresia, mild mandibulofacial dysostosis, auricular malformations, and costovertebral anomalies (hemivertebrae, block vertebra, partial fusion of the ribs, absent ribs). There have been no further descriptions in the literature since 1989. dysostosis