hereditary disease Pilotto syndrome https://rarediseases.info.nih.gov/diseases/4368/pilotto-syndrome cleft lip and palate, congenital heart disease, scoliosis, short stature, and mental retardation Pilotto syndrome is a rare genetic multiple developmental anomalies syndrome, that is characterized by craniofacial anomalies (microcephaly, brachycephaly, craniosynostosis, facial asymmetry, cleft lip, cleft palate, dysmorphic facial features, ear lobe malformations, low hair line), congenital heart defects, hypogenitalism and/or hypogonadism, intellectual disability, scoliosis or kyphoscoliosis, short hypoplastic ribs, failure to thrive, growth delay, short stature and/or micromelia. There have been no further descriptions in the literature since 1975. MONDO:0017331 MEDGEN:419091 Orphanet:2894 MESH:C537400 cleft lip and palate, congenital heart disease, scoliosis, short stature, and intellectual disability UMLS:C2931484