syndromic intellectual disability hereditary disease multiple congenital anomalies/dysmorphic syndrome-intellectual disability 3MC syndrome https://rarediseases.info.nih.gov/diseases/1118/3mc-syndrome https://www.malacards.org/card/3mc_syndrome NANDO:2200792 icd11.foundation:1294329406 OMIMPS:257920 craniofacial-ulnar-renal syndrome 3MC syndrome describes a rare developmental disorder, that unifies the overlapping autosomal recessive disorders previously known as Carnevale, Mingarelli, Malpuech and Michels syndromes, characterized by a spectrum of developmental anomalies that include distinctive facial dysmorphism (i.e. hypertelorism, blepharophimosis, blepharoptosis, highly arched eyebrows), cleft lip and/or palate, craniosynostosis, learning disability, radioulnar synostosis and genital and vesicorenal anomalies. Less common features reported include anterior chamber defects, cardiac anomalies (e.g. ventricular septal defect), caudal appendage, umbilical hernia/omphalocele and diastasis recti. Malpuech-Michels-Mingarelli-Carnevale syndrome MONDO:0017398 MEDGEN:929529 Orphanet:293843 GARD:0001118 UMLS:C4303860 SCTID:720756005 DOID:0060225