lower limb hypertrophy https://github.com/monarch-initiative/mondo/issues/6876 https://www.malacards.org/card/lower_limb_hypertrophy icd11.foundation:601080430 UMLS:C0431928 GARD:0021213 Orphanet:295051 Lower limb hypertrophy is a rare, genetic, non-syndromic developmental defect during embryogenesis characterized by uni- or bilateral overgrowth of lower limbs involving bones and/or soft tissues and resulting in an abnormal increase in leg length and/or width. Hypertrophy presents either as a proportionate overgrowth of entire limb or involves only the proximal or distal parts of it. Phenotype ranges from mild hypertrophy without functional disability to massively hypertrophied limb with knee flexion and ankle equinus contractures and macrodystrophia lipomatosa. Patients may also present vascular abnormalities (e.g. cutaneous angiomas, varicose veins) and myalgia. MONDO:0017477 MEDGEN:451056 disorder of development or morphogenesis