autosomal recessive disease functional neutrophil defect leukocyte adhesion deficiency UMLS:C0272187 Orphanet:2968 Leukocyte adhesion deficiency (LAD) is a primary immunodeficiency characterized by defects in the leukocyte adhesion process, marked leukocytosis and recurrent infections. NCIT:C27874 LAD NANDO:2200755 DOID:6612 GARD:0016616 MONDO:0017570 SCTID:77358003 MEDGEN:124419 NANDO:1200355 icd11.foundation:317341989