syndromic intellectual disability hereditary disease multiple congenital anomalies/dysmorphic syndrome-intellectual disability van Maldergem syndrome https://github.com/monarch-initiative/mondo/issues/5588 https://www.malacards.org/card/van_maldergem_syndrome Van Maldergem Wetzburger Verloes syndrome GARD:0005456 DOID:0060238 MEDGEN:318616 cerebro-facio-articular syndrome of Van Maldergem UMLS:C1832390 Orphanet:314679 MONDO:0017813 A rare multiple congenital anomalies syndrome characterized by mild to severe intellectual disability, a distinctive facial gestalt (blepharophimosis, maxillary hypoplasia, telecanthus, microtia and atresia of the external auditory meatus) as well as skeletal and articular abnormalities (e.g. camptodactyly of the fingers, cutaneous syndactyly, talipes equinovarus, flexion contractures of the proximal interphalangeal joints, hip or elbow subluxation, joint laxity). Affected individuals also present neonatal hypotonia, variable respiratory manifestations, chronic feeding difficulties and gray matter heterotopia. Van Maldergem syndrome OMIMPS:601390