renal cell carcinoma MIT family translocation renal cell carcinoma https://github.com/monarch-initiative/mondo/issues/8567 https://www.malacards.org/card/renal_cell_carcinoma_with_mit_translocations translocation renal cell carcinoma UMLS:C4518356 DOID:0081413 MiT family translocation renal cell carcinoma (t-RCC) is a rare subtype of renal cell carcinoma with recurrent genetic abnormalities, harboring rearrangements of the TFE3 (Xp11 t-RCC) or TFEB [t(6;11) t-RCC] genes. The t(6;11) t-RCC has distinctive histologic features of biphasic appearance with larger epitheloid and smaller eosinophilic cells. The symptoms are usually non-specific and include hematuria, flank pain, palpable abdominal mass and/or systemic symptoms of anemia, fatigue and fever. carcinoma associated with MITF/TFE translocation MONDO:0017886 Orphanet:319308 NCIT:C154494 SCTID:764694005 MEDGEN:1376834 GARD:0017446