disease has feature Abnormal thrombosis cerebrovascular disorder cerebral sinovenous thrombosis https://www.malacards.org/card/cerebral_sinovenous_thrombosis MONDO:0017993 MEDGEN:572643 UMLS:C0338573 A rare but serious cerebrovascular disorder involving thrombosis of the cerebral venous system. It affects children from the newborn period through childhood and adolescence. In childhood CSVT, acute infections of the head and neck such as mastoiditis are most common, followed by chronic underlying diseases such as nephrotic syndrome, cancer, and inflammatory bowel disease. Signs and symptoms are also age related. Seizures and altered mental status are the commonest manifestations in newborns. Headache, vomiting, and lethargy, sometimes with 6th nerve palsy, are the most common symptoms in children and adolescents. GARD:0021485 Orphanet:329217 CSVT