inborn mitochondrial myopathy mitochondrial oxidative phosphorylation disorder adult-onset chronic progressive external ophthalmoplegia with mitochondrial myopathy MONDO:0018002 GARD:0017503 adult-onset CPEO with mitochondrial myopathy Adult-onset chronic progressive external ophthalmoplegia with mitochondrial myopathy is a rare mitochondrial disease characterized by adult onset of progressive external ophthalmoplegia, exercise intolerance, muscle weakness, manifestations of spinocerebellar ataxia (e.g. impaired gait, dysarthria) and mild motor peripheral neuropathy. Respiratory insufficiency has been reported in some cases. UMLS:C4511138 MEDGEN:1393682 Orphanet:329336 SCTID:725464001