disease has feature Autism epilepsy duplication/inversion 15q11 https://rarediseases.info.nih.gov/diseases/5153/isodicentric-chromosome-15-syndrome https://www.malacards.org/card/inverted_duplicated_chromosome_15_syndrome GARD:0005153 duplication/inversion 15q11 MESH:C580205 Invdup(15) tetrasomy 15q MONDO:0018027 Inv dup(15) Isodicentric chromosome 15 syndrome is a chromosome abnormality that affects many different parts of the body. As the name suggests, people with this condition have an extra chromosome (called an isodicentric chromosome 15) which is made of two pieces of chromosome 15 that are stuck together end-to-end. Although the severity of the condition and the associated features vary from person to person, common signs and symptoms include poor muscle tone in newborns; developmental delay; mild to severe intellectual disability; delayed or absent speech; behavioral abnormalities; and seizures. Most cases of isodicentric chromosome 15 syndrome occur sporadically in people with no family history of the condition. Treatment is based on the signs and symptoms present in each person. Orphanet:3306 non-telomeric tetrasomy 15q UMLS:C3711376 Isodicentric 15 chromosome idic(15) inverted duplication 15 chromosome 15q tetrasomy non-distal tetrasomy 15q Isodicentric chromosome 15 syndrome MEDGEN:777984 Duplication/inversion type 15q11 SCTID:723332005 chromosomal disorder