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     xmlns:ns3="http://purl.obolibrary.org/obo/mondo#">
    


    <!-- 
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    //
    // Annotation properties
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#ordo_disorder"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#gard_rare"/>
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.w3.org/2004/02/skos/core#exactMatch"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#orphanet_rare"/>
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#rare"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#ordo_morphological_anomaly"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#nord_rare"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#should_conform_to"/>
    


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    <!-- http://purl.obolibrary.org/obo/RO_0000053 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000053">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#InverseFunctionalProperty"/>
        <rdfs:label>has characteristic</rdfs:label>
        <rdfs:label xml:lang="en">has characteristic</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0004029 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0004029">
        <rdfs:label>disease has feature</rdfs:label>
    </ObjectProperty>
    


    <!-- 
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    <!-- http://purl.obolibrary.org/obo/HP_0000486 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0000486">
        <rdfs:label>Strabismus</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0000156 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0000156">
        <rdfs:label>trigonocephaly</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0015337 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0015337">
        <rdfs:label>isolated craniosynostosis</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0015368 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0015368">
        <rdfs:label>obsolete neuro-ophthalmological disease</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0018065 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0018065">
        <rdfs:label>isolated trigonocephaly</rdfs:label>
        <equivalentClass>
            <Class>
                <intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/MONDO_0000156"/>
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MONDO_0021128"/>
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            </Class>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0000156"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0015337"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0004029"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/HP_0000486"/>
            </Restriction>
        </rdfs:subClassOf>
        <ns3:curated_content_resource rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://www.malacards.org/card/isolated_trigonocephaly</ns3:curated_content_resource>
        <oboInOwl:hasDbXref>GARD:0016626</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MEDGEN:1812049</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NANDO:2201305</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C5575700</oboInOwl:hasDbXref>
        <ns5:IAO_0000115>Isolated trigonocephaly is a nonsyndromic form of craniosynostosis characterized by the premature fusion of the metopic suture.</ns5:IAO_0000115>
        <oboInOwl:hasDbXref>Orphanet:3366</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>non-syndromic metopic craniosynostosis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>nonsyndromic trigonocephaly</oboInOwl:hasExactSynonym>
        <oboInOwl:id>MONDO:0018065</oboInOwl:id>
        <oboInOwl:hasDbXref>OMIMPS:190440</oboInOwl:hasDbXref>
        <skos:exactMatch rdf:resource="http://identifiers.org/medgen/1812049"/>
        <skos:exactMatch rdf:resource="http://linkedlifedata.com/resource/umls/id/C5575700"/>
        <ns3:excluded_subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0015368"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#gard_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#nord_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#ordo_disorder"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#ordo_morphological_anomaly"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#orphanet_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#otar"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#rare"/>
        <ns3:should_conform_to rdf:resource="http://purl.obolibrary.org/obo/mondo/patterns/OMIM_phenotypic_series.yaml"/>
        <skos:exactMatch rdf:resource="http://www.orpha.net/ORDO/Orphanet_3366"/>
        <skos:exactMatch rdf:resource="https://omim.org/phenotypicSeries/PS190440"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0021128 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0021128">
        <rdfs:label>has an isolated presentation</rdfs:label>
    </Class>
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