disease has feature syndromic disease histiocytoma histiocytic and dendritic cell neoplasm non-Langerhans cell histiocytosis Erdheim-Chester disease https://github.com/monarch-initiative/mondo/issues/6742 https://github.com/monarch-initiative/mondo/issues/6878 https://www.malacards.org/card/erdheim_chester_disease NANDO:2200038 ICD9:277.89 ECD MONDO:0018153 MEDGEN:163902 EFO:1000926 Orphanet:35687 icd11.foundation:1395439137 icd11.foundation:146718003 Erdheim-Chester disease (ECD), a non-Langerhans form of histiocytosis, is a multisystemic disease characterized by various manifestations such as skeletal involvement with bone pain, exophthalmos, diabetes insipidus, renal impairment and central nervous system (CNS) and/or cardiovascular involvement. Erdheim Chester Disease UMLS:C0878675 NCIT:C53972 DOID:4329 MESH:D031249 This term's classification was reviewed in the context of the Strategic Refinement project (2023) and was determined to be excluded from the 'connective tissue disorder' (MONDO:0018153) ontology branch (https://orcid.org/0000-0002-1780-5230) lipoid granulomatosis Erdheim-Chester disease polyostotic sclerosing histiocytosis ONCOTREE:ECD Erdheim Chester disease MedDRA:10060801 SCTID:699537002 lipogranulomatosis GARD:0006369 NORD:1102