LMNA-related cardiocutaneous progeria syndrome https://www.malacards.org/card/lmna_related_cardiocutaneous_progeria_syndrome GARD:0021555 A rare, genetic, premature aging syndrome characterized by adulthood-onset cutaneous manifestations that result in a prematurely aged appearance (i.e. premature thinning and graying of scalp hair, loss of subcutaneous fat, tightening of skin) associated with prominent cardiovascular manifestations, such as accelerated atherosclerosis, calcific valve disease, and cardiomyopathy. Patients present loss of eyebrows and eyelashes in childhood and have a predisposition to develop malignancies. Orphanet:363618 MEDGEN:1667690 UMLS:C4750858 MONDO:0018203 LCPS premature aging syndrome cardiogenetic disease