syndromic disease developmental anomaly of metabolic origin CADDS https://github.com/monarch-initiative/mondo/issues/5809 https://www.malacards.org/card/cadds CADDS is a rare, genetic, neurometabolic disease characterized by severe intrauterine growth retardation, failure to thrive, profound neonatal hypotonia, severe global development delay, elevated very long chain fatty acids in plasma, and neonatal cholestasis leading to hepatic failure and death. Other features include ocular abnormalities (e.g. blindness and cataracts), sensorineural deafness, seizures, and abnormal brain morphology (notably delayed CNS myelination and ventriculomegaly). CADDS Zellweger-like contiguous gene deletion syndrome MONDO:0018247 GARD:0012472 Orphanet:369942 contiguous ABCD1 DXS1357E deletion syndrome leukodystrophy peroxisomal disease