disease arises from feature disease has basis in feature disease has major feature dementia iron metabolism disease neuroaxonal dystrophy movement disorder neurodegenerative disease hereditary dementia neurodegeneration with brain iron accumulation https://www.malacards.org/card/neurodegeneration_with_brain_iron_accumulation Neurodegeneration with brain iron accumulation (NBIA, formerly Hallervorden-Spatz syndrome) encompasses a group of rare neurodegenerative disorders characterized by progressive extrapyramidal dysfunction (dystonia, rigidity, choreoathetosis), iron accumulation in the brain and the presence of axonal spheroids, usually limited to the central nervous system. MEDGEN:444156 icd11.foundation:440483530 DOID:0110734 MONDO:0018307 NANDO:2100241 OMIMPS:234200 Orphanet:385 Editor note: check relationship to PKAN GARD:0011899 neurodegeneration with brain iron accumulation UMLS:C2931845 MESH:C538421 NBIA inborn errors of metabolism inherited neurodegenerative disorder