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    <!-- http://purl.obolibrary.org/obo/RO_0004025 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0004025">
        <rdfs:label>disease causes dysfunction of</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0004026 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0004026">
        <rdfs:label>disease has location</rdfs:label>
    </ObjectProperty>
    


    <!-- 
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    <!-- http://purl.obolibrary.org/obo/CL_0000453 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000453">
        <rdfs:label>Langerhans cell</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0002332 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0002332">
        <rdfs:label>splenic disorder</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0002637 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0002637">
        <rdfs:label>histiocytosis</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0004805 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0004805">
        <rdfs:label>leukocyte disorder</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0018310 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0018310">
        <rdfs:label>Langerhans cell histiocytosis</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0002637"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0004805"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0020082"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0024627"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0004026"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000453"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0004025"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000453"/>
            </Restriction>
        </rdfs:subClassOf>
        <ns3:curated_content_resource rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://www.malacards.org/card/langerhans_cell_histiocytosis_2</ns3:curated_content_resource>
        <oboInOwl:hasRelatedSynonym>Lch</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>OMIM:604856</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:1000318</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Langerhans-cell histiocytosis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>SCTID:65399007</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Langerhans cell histiocytosis, Not otherwise specified</oboInOwl:hasExactSynonym>
        <ns5:IAO_0000115>Langerhans cell histiocytosis (LCH) is a systemic disease associated with the proliferation and accumulation (usually in granulomas) of Langerhans cells in various tissues.</ns5:IAO_0000115>
        <oboInOwl:hasExactSynonym>histiocytosis X</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>ICDO:9751/3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:9753/1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:9751/1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MEDGEN:5568</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C3107</oboInOwl:hasDbXref>
        <oboInOwl:id>MONDO:0018310</oboInOwl:id>
        <rdfs:comment>We follow NCIT in classifying this as a neoplasm but this may be revisited</rdfs:comment>
        <oboInOwl:hasDbXref>ICD9:202.5</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GARD:0006858</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Langerhans cell granulomatosis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>DOID:2571</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9:277.89</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Orphanet:389</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>icd11.foundation:1388720498</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>LCH</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>icd11.foundation:216625985</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NORD:1348</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Langerhans cell histiocytosis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>MedDRA:10069698</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Langerhans cell histiocytosis, NOS</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>ICDO:9752/1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ONCOTREE:LCH</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:9754/3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0019621</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NANDO:2200031</oboInOwl:hasDbXref>
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        <skos:exactMatch rdf:resource="http://identifiers.org/medgen/5568"/>
        <skos:exactMatch rdf:resource="http://identifiers.org/snomedct/65399007"/>
        <skos:exactMatch rdf:resource="http://linkedlifedata.com/resource/umls/id/C0019621"/>
        <skos:exactMatch rdf:resource="http://purl.obolibrary.org/obo/DOID_2571"/>
        <ns3:excluded_subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0002332"/>
        <skos:exactMatch rdf:resource="http://purl.obolibrary.org/obo/NCIT_C3107"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#disease_grouping"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#gard_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#ncit_rare"/>
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        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#ordo_disorder"/>
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        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#otar"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#rare"/>
        <skos:exactMatch rdf:resource="http://www.ebi.ac.uk/efo/EFO_1000318"/>
        <skos:exactMatch rdf:resource="http://www.orpha.net/ORDO/Orphanet_389"/>
        <skos:exactMatch rdf:resource="https://omim.org/entry/604856"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0020082 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0020082">
        <rdfs:label>dendritic cell tumor</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0024627 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0024627">
        <rdfs:label>phagocytic cell dysfunction</rdfs:label>
    </Class>
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