osteonecrosis avascular necrosis https://www.malacards.org/card/avascular_necrosis NCIT:C34841 Orphanet:399164 UMLS:C0027543 AVN Necrotic changes in the bone tissue due to interruption of blood supply. Most often affecting the epiphysis of the long bones, the necrotic changes result in the collapse and the destruction of the bone structure. GARD:0021658 MEDGEN:10200 SCTID:397758007 MONDO:0018373 avascular necrosis of bone