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    <!-- http://purl.obolibrary.org/obo/MONDO_0018433 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0018433">
        <rdfs:label>acute myeloid leukemia with t(6;9)(p23;q34)</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0018874"/>
        <ns3:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/monarch-initiative/mondo/issues/8583</ns3:IAO_0000233>
        <ns4:curated_content_resource rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://www.malacards.org/card/acute_myeloid_leukemia_with_t69_p23q341</ns4:curated_content_resource>
        <ns3:IAO_0000115>Acute myeloid leukemia with t(6;9)(p23;q34) is a rare subtype of acute myeloid leukemia with recurrent genetic abnormalities characterized by clonal proliferation of poorly differentiated myeloid blasts in the bone marrow, blood, or other tissues in patients who present the t(6;9)(p23;q34) translocation. Frequently associated with multilineage bone marrow dysplasia, it usually presents with anemia, thrombocytopenia (often pancytopenia), and other nonspecific symptoms related to ineffective hematopoesis (fatigue, bleeding and bruising, recurrent infections, bone pain) and/or extramedullary site involvement (gingivitis, splenomegaly). Basophilia, as well as poor response to chemotherapy, has been reported.</ns3:IAO_0000115>
        <ns3:IAO_0006012>2025-04-01</ns3:IAO_0006012>
        <oboInOwl:hasDbXref>MEDGEN:1376401</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C4518837</oboInOwl:hasDbXref>
        <oboInOwl:id>MONDO:0018433</oboInOwl:id>
        <oboInOwl:hasDbXref>GARD:0021710</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Orphanet:402014</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>AML with t(6;9)(p23;q34)</oboInOwl:hasExactSynonym>
        <rdfs:comment>Reason of obsoletion: duplicate. This will be merged with MONDO:0100382 acute myeloid leukemia, t(6;9)(p23;q34.1)</rdfs:comment>
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    <!-- http://purl.obolibrary.org/obo/MONDO_0018874 -->

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        <rdfs:label>acute myeloid leukemia</rdfs:label>
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