renal cell carcinoma acquired cystic disease-associated renal cell carcinoma https://www.malacards.org/card/acquired_cystic_disease_associated_renal_cell_carcinoma MEDGEN:1644241 UMLS:C4707179 GARD:0021722 NCIT:C157718 Orphanet:404514 Acquired cystic disease-associated renal cell carcinoma is a rare subtype of renal cell carcinoma, occurring in the context of end-stage kidney disease and acquired cystic kidney disease, characterized by a usually well circumscribed, solid, multifocal, bilateral tumor with inter- or intracellular microlumen formation (leading to cribiform architecture). Tumors are often diagnosed incidentally in early stages, although complications caused by renal cysts (dull flank or abdominal pain, fever) or renal parenchymal bleeding may mask the underlying neoplastic process. Most have an indolent behavior. MONDO:0018449