autoimmune disorder of endocrine system hyperinsulinemic hypoglycemia insulin autoimmune syndrome https://rarediseases.info.nih.gov/diseases/10808/insulin-autoimmune-syndrome https://www.malacards.org/card/hirata_disease GARD:0010808 ICD9:279.49 DOID:0040100 MONDO:0018465 Insulin autoimmune syndrome is a rare condition that causes low blood sugar (hypoglycemia). This occurs because the body begins to make a specific kind of protein called antibodies to attack insulin. Insulin is a naturally occurring hormone that is responsible for keeping blood sugar at a normal level. When blood sugar levels get too high, insulin helps to store the sugar for future use. People affected by insulin autoimmune syndrome have antibodies that attack insulin, causing it to work too hard and the level of blood sugar to become too low. Insulin autoimmune syndrome most often begins during adulthood. MEDGEN:678528 SCTID:408539000 Hirata disease insulin autoimmune hypoglycemia UMLS:C0854359 Orphanet:411593