disease arises from feature disease has basis in feature Obstructive sleep apnea Autoimmunity Parasomnia autoimmune disorder of central nervous system sleep-wake disorder brain disorder autoimmune encephalopathy with parasomnia and obstructive sleep apnea https://www.malacards.org/card/autoimmune_encephalopathy_with_parasomnia_and_obstructive_sleep_apnea MEDGEN:1644256 anti-IgLON5 syndrome Orphanet:420789 UMLS:C4707562 anti-IgLON5 disease GARD:0021749 MONDO:0018489 Autoimmune encephalopathy with parasomnia and obstructive sleep apnea is a rare neurologic disorder characterized by a unique non-REM and REM parasomnia with sleep breathing dysfunction, gait instability and repetitive episodes of respiratory insufficiency, as well as autoantibodies against IgLON5. Patients may present stridor, chorea, limb ataxia, abnormal ocular movements, and bulbar symptoms (i.e. dysphagia, dysarthria, episodic central hypoventilation) with normal brain MRI. Excessive day sleepiness and cognitive deterioration have also been reported. SCTID:765751002