has material basis in germline mutation in ABCD1 X-linked disease adrenal gland disorder chronic primary adrenal insufficiency hereditary dementia adrenoleukodystrophy https://github.com/monarch-initiative/mondo/issues/2632 https://github.com/monarch-initiative/mondo/issues/4521 https://github.com/monarch-initiative/mondo/issues/7924 https://www.malacards.org/card/adrenoleukodystrophy icd11.foundation:1085655586 NANDO:2200576 MESH:D000326 adrenoleukodystrophy MedDRA:10051260 adrenoleukodystrophy, X-linked NCIT:C61252 DOID:10588 adrenomyeloneuropathy, adult A peroxisomal disorder resulting in cerebral demyelination, axonal dysfunction in the spinal cord leading to spastic paraplegia, adrenal insufficiency and in some cases testicular insufficiency. GARD:0005758 UMLS:C0162309 Bronze-Schilder disease OMIM:300100 MEDGEN:57667 X-linked ALD NANDO:1200165 NORD:736 X-Linked Adrenoleukodystrophy Siemerling-Creutzfeldt disease adrenoleukodystrophy, X-linked recessive ALD diffuse cerebral sclerosis of Schilder Orphanet:43 X-linked adrenoleukodystrophy X-ALD adrenomyeloneuropathy, adult, X-linked recessive MONDO:0018544 ABCD1 deficiency leukodystrophy disorder of peroxisomal beta oxidation disorder of peroxisomal transporter