disease has major feature dementia ITM2B amyloidosis https://www.malacards.org/card/itm2b_amyloidosis MEDGEN:82800 ITM2B-related amyloidosis MONDO:0018591 ITM2B-related cerebral amyloid angiopathy UMLS:C0268393 Orphanet:439254 icd11.foundation:503091580 GARD:0017741 ICD9:277.39 SCTID:45639009 familial cerebral amyloid angiopathy hereditary amyloidosis inherited neurodegenerative disorder