syndromic disease Holmes-Adie syndrome https://www.malacards.org/card/adie_pupil MONDO:0018690 DOID:11549 Orphanet:454718 MESH:D000270 tonic, sluggishly reacting pupil and hypoactive or absent tendon reflexes NORD:735 Holmes-Adie syndrome GARD:0005749 Adie Syndrome NCIT:C34357 Adie syndrome EFO:0004126 tonic pupil-tendon areflexia syndrome tonic pupil Adie pupil A rare syndrome characterized by an abnormally dilated pupil, hypoflexia, and diaphoresis. The syndrome is usually caused by a viral or bacterial infection. The abnormally dilated pupil is caused by damage to postganglionic parasympathetic fibers innervating the eye. MEDGEN:138 OMIM:103100 UMLS:C0001519 Adie's pupil SCTID:24225004