has characteristic has characteristic vascular disorder congenital portosystemic shunt https://github.com/monarch-initiative/mondo/issues/4069 https://github.com/monarch-initiative/mondo/issues/6740 https://github.com/monarch-initiative/mondo/issues/6876 https://www.malacards.org/card/congenital_portosystemic_shunt MEDGEN:712860 MONDO:0018811 icd11.foundation:682625970 Congenital portosystemic shunt is a rare, congenital anomaly of the great veins characterized by an abnormal communication between one or more veins of the portal and the caval systems, resulting in complete or partial diversion of the portal blood away from the liver to the systemic circulation. Clinical manifestations include liver atrophy, hypergalactosemia without uridine diphosphate enzyme deficiency, hyperammonemia, encephalopathy (resulting in learning disabilities, extreme fatigability and seizures), pulmonary hypertension, hypoxemia from hepatopulmonary syndrome and benign or malignant tumors. Orphanet:480531 congenital portosystemic venous fistula UMLS:C1290495 GARD:0021979 congenital disorder of development or morphogenesis