disease shares features of mitochondrial oxidative phosphorylation disorder Zellweger-like syndrome without peroxisomal anomalies https://www.malacards.org/card/zellweger_like_syndrome_without_peroxisomal_anomalies MONDO:0018861 An extremely rare mitochondrial disorder characterized by facial dysmorphism similar to that seen in Zellweger syndrome, such as frontal bossing, high forehead, upslanting palpebral fissures, hypoplastic supraorbital ridges, and epicanthal folds, and in addition, pale skin, profound hypotonia, developmental delay, and minor metabolic anomalies. No peroxysomal defects, however, have been reported. Transmission is thought to be autosomal recessive. GARD:0018841 icd11.foundation:697302760 AHN-Lerman-Sagie syndrome UMLS:C4305104 Orphanet:50812 MEDGEN:930773 SCTID:718880003 Zellweger spectrum disorders