focal palmoplantar keratoderma striate palmoplantar keratoderma https://github.com/monarch-initiative/mondo/issues/6749 https://github.com/monarch-initiative/mondo/issues/6877 https://www.malacards.org/card/keratosis_palmoplantaris_striata UMLS:C4707237 keratosis palmoplantaris varians of Wachters icd11.foundation:1171134598 DOID:0081105 Striate palmoplantar keratoderma is an isolated, focal, hereditary palmoplantar keratoderma characterized by linear hyperkeratosis along the flexor aspect of the fingers and on palms, as well as focal hyperkeratosis of the plantar skin. Patients present with painful thickening of the skin on palms and soles, with occasional fissuring, blistering and hyperhidrosis. Rarely, hyperkeratosis on other areas may be seen (knees, dorsal aspects of the digits). Histopatologically, widened intercellular spaces between keratinocytes are observed. MEDGEN:1631598 Orphanet:50942 keratosis palmoplantaris striata et areata SCTID:764958008 keratosis palmoplantaris striata MONDO:0018865 GARD:0015016