<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/MONDO?iri=http://purl.obolibrary.org/obo/MONDO_0018874"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:ns5="http://purl.obolibrary.org/obo/mondo#"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:skos="http://www.w3.org/2004/02/skos/core#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#disease_grouping"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#gard_rare"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#otar"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#curated_content_resource"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#ordo_group_of_disorders"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000233"/>
    <AnnotationProperty rdf:about="http://www.w3.org/2004/02/skos/core#exactMatch"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#doid_rare"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#clingen"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#omim_susceptibility"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#rare"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#nord_rare"/>
    <AnnotationProperty rdf:about="http://www.w3.org/2004/02/skos/core#closeMatch"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0000053 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000053">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#InverseFunctionalProperty"/>
        <rdfs:label>has characteristic</rdfs:label>
        <rdfs:label xml:lang="en">has characteristic</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0004029 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0004029">
        <rdfs:label>disease has feature</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/HP_0001903 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0001903">
        <rdfs:label>Anemia</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0002280 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0002280">
        <rdfs:label>anemia</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0004643 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0004643">
        <rdfs:label>myeloid leukemia</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0010643 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0010643">
        <rdfs:label>acute leukemia</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0018874 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0018874">
        <rdfs:label>acute myeloid leukemia</rdfs:label>
        <equivalentClass>
            <Class>
                <intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/MONDO_0004643"/>
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000389"/>
                    </Restriction>
                </intersectionOf>
            </Class>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0004643"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0010643"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0004029"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MONDO_0002280"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0004029"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/HP_0001903"/>
            </Restriction>
        </rdfs:subClassOf>
        <ns4:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/monarch-initiative/mondo/issues/4521</ns4:IAO_0000233>
        <ns4:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/monarch-initiative/mondo/issues/9097</ns4:IAO_0000233>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://rarediseases.info.nih.gov/diseases/12757/acute-myeloid-leukemia</rdfs:seeAlso>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://rarediseases.info.nih.gov/diseases/537/acute-non-lymphoblastic-leukemia</rdfs:seeAlso>
        <ns5:curated_content_resource rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://www.malacards.org/card/leukemia_acute_myeloid</ns5:curated_content_resource>
        <oboInOwl:hasDbXref>MEDGEN:9730</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9:205.00</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>acute Nonlymphocytic leukaemia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>GARD:0012757</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>acute myelogenous leukemia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>acute myelocytic leukemia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>MedDRA:10000880</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>acute myeloid leukemia (AML)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>acute granulocytic leukemia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>hematopoeitic - acute Myleogenous leukemia (AML)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>OMIM:601626</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>acute myeloblastic leukemia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C0023467</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>acute non lymphoblastic leukemia</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>acute myeloid leukemia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>acute nonlymphocytic leukaemia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym>acute non lymphoblastic leukaemia</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>ONCOTREE:AML</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>myeloid leukemia, acute</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>leukemia, acute myeloid, susceptibility to, autosomal dominant, somatic mutation</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>Acute myeloid leukemia (AML) is a group of neoplasms arising from precursor cells committed to the myeloid cell-line differentiation. All of them are characterized by clonal expansion of myeloid blasts. AML manifests by fever, pallor, anemia, hemorrhages and recurrent infections.</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym>myeloid leukemia, acute, M4/M4Eo subtype, somatic</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>acute nonlymphocytic leukemia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym>leukemia, acute myeloid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>MESH:D015470</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:91861009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C92.0</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>leukemia, acute myeloid, autosomal dominant, somatic mutation</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>Orphanet:519</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C3171</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9:205.0</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>AML</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>acute myelogenous leukemias</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>hematopoeitic - acute Myleogenous leukaemia (AML)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>acute Nonlymphocytic leukemia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>ICDO:9861/3</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>ANLL</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>leukemia, acute myeloid, somatic</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>DOID:9119</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NORD:1905</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>leukemia, acute myeloid, reduced survival in, somatic</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>acute myeloid leukemia, somatic</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>acute myeloid leukaemia (AML)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>acute granulocytic leukaemia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>acute myelocytic leukaemia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>EFO:0000222</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>AML - acute myeloid leukemia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>AML - acute myeloid leukaemia</oboInOwl:hasExactSynonym>
        <oboInOwl:id>MONDO:0018874</oboInOwl:id>
        <oboInOwl:hasExactSynonym>leukemia, myelocytic, acute</oboInOwl:hasExactSynonym>
        <skos:closeMatch rdf:resource="http://identifiers.org/meddra/10000880"/>
        <skos:exactMatch rdf:resource="http://identifiers.org/medgen/9730"/>
        <skos:exactMatch rdf:resource="http://identifiers.org/mesh/D015470"/>
        <skos:exactMatch rdf:resource="http://identifiers.org/snomedct/91861009"/>
        <skos:exactMatch rdf:resource="http://linkedlifedata.com/resource/umls/id/C0023467"/>
        <skos:exactMatch rdf:resource="http://purl.bioontology.org/ontology/ICD10CM/C92.0"/>
        <skos:exactMatch rdf:resource="http://purl.obolibrary.org/obo/DOID_9119"/>
        <skos:exactMatch rdf:resource="http://purl.obolibrary.org/obo/NCIT_C3171"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#clingen"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#disease_grouping"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#doid_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#gard_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#nord_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#omim_susceptibility"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#ordo_group_of_disorders"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#otar"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#rare"/>
        <skos:exactMatch rdf:resource="http://www.ebi.ac.uk/efo/EFO_0000222"/>
        <skos:exactMatch rdf:resource="http://www.orpha.net/ORDO/Orphanet_519"/>
        <skos:exactMatch rdf:resource="https://omim.org/entry/601626"/>
        <ns5:curated_content_resource rdf:resource="https://search.clinicalgenome.org/kb/conditions/MONDO:0018874"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000389 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000389">
        <rdfs:label>acute</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



