arteriovenous hemangioma/malformation skin hemangioma hereditary neoplastic syndrome Cobb syndrome https://rarediseases.info.nih.gov/diseases/11892/cobb-syndrome https://www.malacards.org/card/cobb_syndrome UMLS:C0346068 Cobb syndrome is defined by the association of vascular cutaneous (venous or arteriovenous), muscular (arteriovenous), osseous (arteriovenous) and medullary (arteriovenous) lesions at the same metamere or spinal segment. This segmental distribution may involve one or many of the 31 metameres present in humans. Only 16% of the medullary lesions are multiple and have a clearly metameric distribution. GARD:0011892 spinal arteriovenous metameric syndrome ICD9:239.2 Cobb's syndrome SAMS 1-31 Orphanet:53721 MONDO:0018893 MedDRA:10068841 icd11.foundation:1451924695 NCIT:C4485 MEDGEN:91079 cutaneomeningospinal angiomatosis SCTID:254774003 skin vascular disease hereditary skin disorder