neoplasm of mature B-cells aggressive B-cell non-Hodgkin lymphoma diffuse large B-cell lymphoma https://github.com/monarch-initiative/mondo/issues/9097 https://rarediseases.info.nih.gov/diseases/3178/diffuse-large-B-cell-lymphoma https://www.malacards.org/card/diffuse_large_b_cell_lymphoma ICDO:9680/3 ICD9:200.7 MESH:D016403 NCIT:C8851 MONDO:0018905 Diffuse large B-cell lymphoma is the most common subtype of non-Hodgkin lymphoma (NHL) in adults characterized by a median age of presentation in the sixth decade of life (but also rarely occurring in adolescents and children) with the initial presentation being single or multiple rapidly growing masses (that may or may not be painful) in nodal or extranodal sites (such as thyroid, skin, breast, gastrointestinal tract, testes, bone, or brain) and that can be accompanied by symptoms of fever, night sweats and weight loss. DLBCL has an aggressive disease course, with the elderly having a poorer prognosis than younger patients, and with relapses being common. ICD10CM:C83.3 DOID:0050745 MEDGEN:86954 icd11.foundation:1946973604 diffuse large B-cell lymphoma DLBCL MedDRA:10012818 UMLS:C0079744 EFO:0000403 Orphanet:544 GARD:0003178