disease has basis in disruption of disease caused by disruption of disease has feature methylcrotonoyl-CoA carboxylase activity Hypotonia Skeletal muscle atrophy 3-methylcrotonyl-CoA carboxylase deficiency https://github.com/monarch-initiative/mondo/issues/4985 https://www.malacards.org/card/3_methylcrotonyl_coa_carboxylase_deficiency MCC deficiency UMLS:C4551505 MEDGEN:1633312 3-MCC deficiency Methylcrotonyl-CoA carboxylase deficiency 3-methylcrotonyl-CoA carboxylase deficiency (3-MCCD) is an inherited disorder of leucine metabolism characterized by a highly variable clinical picture ranging from metabolic crisis in infancy to asymptomatic adults. 3-methylcrotonylglycinuria Orphanet:6 SCTID:13144005 3-methylcrotonyl-CoA carboxylase deficiency DOID:0050710 MONDO:0018950 MCCD OMIMPS:210200 NANDO:2200495 GARD:0010954 NCIT:C98674 classic organic aciduria