neural tube defect skeletal dysplasia parietal foramina https://www.malacards.org/card/parietal_foramina symmetric parietal foramina enlarged parietal foramina icd11.foundation:905361904 OMIMPS:168500 parietal foramina hereditary cranium bifidum GARD:0016662 Orphanet:60015 fenestrae parietales symmetricae DOID:0060285 MONDO:0018953 SCTID:718099006 HP:0002697 MESH:C566826 foramina parietalia permagna Enlarged parietal foramina (EPF) is a developmental defect, characterized by variable intramembranous ossification defects of the parietal bones, which is either asymptomatic, symptomatic (headaches, nausea, vomiting, intellectual disability) or associated with other pathologies. catlin marks hereditary neurological disease