pure hair and nail ectodermal dysplasia GARD:0016680 hair-nail ectodermal dysplasia Orphanet:69084 PHNED Pure hair and nail ectodermal dysplasia is characterized by the association of onychodystrophy and severe hypotrichosis, which is mainly limited to the scalp but may also affect the eyelashes and eyebrows. Less than 20 cases have been reported so far. The mode of transmission is autosomal dominant. MEDGEN:1875649 DOID:0111655 HNED UMLS:C5979821 MONDO:0019071 ectodermal dysplasia syndrome