disease arises from structure disease arises from alteration in structure carcinoma adenocarcinoma of gallbladder and extrahepatic biliary tract cholangiocarcinoma Cholangiocar.- intra/extrahepatic MedDRA:10008593 GARD:0009304 ONCOTREE:CHOL MedDRA:10004593 A carcinoma that arises from the intrahepatic biliary tree (intrahepatic cholangiocarcinoma) or from the junction, or adjacent to the junction, of the right and left hepatic ducts (hilar cholangiocarcinoma). Grossly, the malignant lesions are solid, nodular, and grayish. Morphologically, the vast majority of cases are adenocarcinomas. Signs and symptoms include malaise, weight loss, right upper quadrant abdominal pain, and night sweats. Early detection is difficult and the prognosis is generally poor. EFO:0005221 cholangiocarcinoma, intrahepatic and extrahepatic bile ducts (adenocarcinoma) MESH:D018281 Cholangiocellular carcinoma cholangiocarcinoma, malignant ICDO:8160/3 MEDGEN:60210 intrahepatic bile duct cancer (cholangiocarcinoma) DOID:4947 Orphanet:70567 NCIT:C4436 CC NORD:926 CCA bile duct cancer cholangiocarcinoma MONDO:0019087 icd11.foundation:2110597275 SCTID:312104005 UMLS:C0206698 bile duct