non-familial restrictive cardiomyopathy Loeffler endocarditis https://www.malacards.org/card/loeffler_endocarditis GARD:0018929 MedDRA:10052841 Loeffler's endocarditis is a rare restrictive cardiomyopathy characterized by hypereosinophilia and fibrous thickening of the endocardium, with usually large thrombi against the ventricle walls, that can lead to cardiovascular complications such as heart failure and thromboembolism. It manifests with symptoms like edema, fatigue and shortness of breath. It is usually secondary to eosinophil-associated tissue damage and is associated with idiopathic hypereosinophilic syndrome, chronic eosinophilic leukemia, carcinoma, or lymphoma. NCIT:C27044 Orphanet:75566 eosinophilic endomyocardial disease MEDGEN:104788 icd11.foundation:1223390562 DOID:396 eosinophilic endocarditis SCTID:449829009 MONDO:0019159 UMLS:C0206143