disease disrupts disease causes disruption of gonadotropin secretion precocious puberty hereditary disease precocious puberty in female central precocious puberty https://www.malacards.org/card/central_precocious_puberty https://www.malacards.org/card/rare_central_precocious_puberty EFO:0009029 gonadotropin-dependant precocious puberty Orphanet:650063 MESH:C562787 SCTID:237816004 ICD9:259.1 UMLS:C0342543 MEDGEN:90985 Central precocious puberty (CPP), also referred to as gonadotropin dependent precocious puberty, is an endocrine-related developmental disease characterized by the onset of pubertal changes, with development of secondary sexual characteristics and accelerated growth and bone maturation, before the normal age of puberty (8 years in girls and 9 years in boys). OMIMPS:176400 NANDO:1200381 precocious puberty, central GARD:0016546 NANDO:2200377 DOID:0112308 gonadotropin-dependent precocious puberty Orphanet:759 icd11.foundation:1749914533 MONDO:0019165